This course is designed to improve the learner’s ability to understand cellular physiology and alterations in structure and function resulting from the action of stressors on the human body at the cellular level. Physiological, pathophysiological, psychobiological, and pharmacological concepts are examined that provide a foundation for understanding the pathophysiology of disease and the rationale for treatment including pharmacologic therapy that serve as a basis for critical thinking and decision making in the planning and managing of care for individuals across the life span are examined.